What is this drug used for?
• It is used to treat HIV infection.
Frequently reported side effects of this drug
• Loss of strength and energy
• Trouble sleeping
• Trouble focusing
• Abnormal dreams
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin or eyes
• Depression like thoughts of suicide, anxiety, emotional instability, agitation, irritability, panic attacks, mood changes, behavioral changes, or confusion
• Change in body fat
• Behavioral changes
• Sensing things that seem real but are not
• Trouble with memory
• Mood changes
• Change in balance
• Abnormal movements
• Abnormal heartbeat
• Fast heartbeat
• Severe dizziness
• Passing out
• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
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Medication Safety Issues
High alert medication:
This medication is in a class the Institute for Safe Medication Practices (ISMP) includes among its list of drug classes that have a heightened risk of causing significant patient harm when used in error.
Storage and Stability
Store at 25°C (77°F); excursion permitted to 15°C to 30°C (59°F to 86°F).
Cardiovascular: Prolonged QT interval on ECG
Dermatologic: Erythema multiforme, pruritus, skin rash
Endocrine & metabolic: Hyperglycemia, increased amylase, increased gamma-glutamyl transferase, increased HDL cholesterol, increased serum cholesterol, increased serum triglycerides
Gastrointestinal: Abdominal pain, anorexia, diarrhea, dyspepsia, nausea, vomiting
Hematologic & oncologic: Neutropenia
Hepatic: Increased serum alanine aminotransferase (incidence higher with hepatitis B and/or C coinfection), increased serum aspartate aminotransferase (incidence higher with hepatitis B and/or C coinfection)
Nervous system: Abnormal dreams, anxiety, central nervous system toxicity, depression, dizziness, drowsiness, fatigue, hallucination, headache, insomnia, lack of concentration, nervousness, pain, severe depression
Rare: Aggressive behavior, agitation, arthralgia, asthenia, ataxia, catatonia, cerebellar ataxia, constipation, delusion, dyspnea, emotional lability, encephalopathy, flushing, fulminant hepatitis, gynecomastia, hepatic failure, hepatitis, hypersensitivity reaction, hypoesthesia, immune reconstitution syndrome, lipotrophy, loss of balance, malabsorption, mania, myalgia, myopathy, neuropathy, palpitations, pancreatitis, paranoid ideation, paresthesia, photodermatitis, psychoneurosis, psychosis, redistribution of body fat, seizure, Stevens-Johnson syndrome, suicidal ideation, suicidal tendencies, tinnitus, tremor, vertigo, visual disturbance