What is this drug used for?
• It is used to treat hiccups.
• It is used to treat tetanus.
• It is used to treat problems with how one acts.
• It is used to treat acute intermittent porphyria.
• It is used to treat mania.
• It is used to treat upset stomach and throwing up.
• It is used to treat schizophrenia.
• It is used to ease anxiety before surgery.
• It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
• Dry mouth
• Stuffy nose
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Neuroleptic malignant syndrome like fever, muscle cramps or stiffness, dizziness, severe headache, confusion, change in thinking, fast heartbeat, abnormal heartbeat, or sweating a lot.
• High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit.
• Low blood sugar like dizziness, headache, fatigue, feeling weak, shaking, fast heartbeat, confusion, increased hunger, or sweating.
• Tardive dyskinesia like unable to control body movements; tongue, face, mouth, or jaw sticking out; mouth puckering; or puffing cheeks.
• Fast heartbeat
• Yellow skin
• Abnormal heartbeat
• Erection that lasts more than 4 hours
• Abnormal movements
• Change in balance
• Muscle weakness
• Difficulty swallowing
• Difficulty speaking
• Passing out
• Difficulty moving
• Behavioral changes
• Swelling of arms or legs
• Vision changes
• Enlarged breasts
• Nipple discharge
• Sexual dysfunction
• No menstrual periods
• Difficult urination
• Unable to pass urine
• Severe loss of strength and energy
• Trouble sleeping
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
(klor PROE ma zeen)
Medication Safety Issues
ChlorproMAZINE may be confused with chlordiazePOXIDE, chlorproPAMIDE, clomiPRAMINE, prochlorperazine, promethazine
Thorazine may be confused with thiamine, thioridazine
Storage and Stability
Oral: Store at 20°C to 25°C (68°F to 77°F); protect from light and moisture.
Injection solution: Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light and freezing. A slightly yellowed solution does not indicate potency loss, but a markedly discolored solution should be discarded.
Cardiovascular: ECG abnormality (nonspecific QT changes), orthostatic hypotension, syncope, tachycardia
Central nervous system: Brain edema, catatonic-like state, dizziness, drowsiness, dystonia, extrapyramidal reaction, hyperpyrexia, neuroleptic malignant syndrome, parkinsonism, psychotic symptoms, restlessness, tardive dyskinesia, tardive dystonia
Dermatologic: Contact dermatitis, cutaneous lupus erythematosus (Pavlidakey 1985), skin photosensitivity, skin pigmentation (slate gray)
Endocrine & metabolic: Weight gain
Gastrointestinal: Atony of colon, constipation, increased appetite, nausea, obstipation, paralytic ileus, xerostomia
Genitourinary: Breast engorgement, ejaculatory disorder, false positive pregnancy test, impotence, lactation, priapism, urinary retention
Hematologic & oncologic: Agranulocytosis, aplastic anemia, eosinophilia, hemolytic anemia, immune thrombocytopenia, leukopenia
Hypersensitivity: Nonimmune anaphylaxis
Neuromuscular & skeletal: Lupus-like syndrome (Pavlidakey 1985)
Ophthalmic: Corneal deposits, lens disease (deposits), miosis, mydriasis, star-shaped cataract, visual impairment
Respiratory: Nasal congestion
Miscellaneous: Low fever
Postmarketing: Abnormal proteins in cerebrospinal fluid, amenorrhea, angioedema, asthma, epithelial keratopathy, exfoliative dermatitis, glycosuria, gynecomastia, hyperglycemia, hypoglycemia, laryngeal edema, pancytopenia, peripheral edema, retinitis pigmentosa, seizure